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Research supervisor: 
Erdem Dashinimaev
PhD

Supervisor’s research interests: 
 
  • Human induced pluripotent stem cells.
  •  Direct reprogramming of human somatic cells.
  •  Genome editing using CRISPR/Cas9 methods.
  •  CRISPR-a screening of reprogramming factors.
  •  Single cell RNA-seq analysis.
 

Research highlights:
  •  A well-equipped scientific laboratory, which has almost all the necessary tools to perform work on the declared topics.
  •  Young friendly team of like-minded people, favorable atmosphere of creativity.
  •  Setting up the appropriate level of research work for publication in international scientific journals. 

Supervisor’s specific requirements:
  •  Level of knowledge of two languages – Russian and English at a confident level (or only English, but at an excellent level).
  •  Residence in MIPT “Zuzino” hostel, because the laboratory is located near the metro station “Troparevo” (south-west) and the travel time from Dolgoprudny takes more than 1.5 hours.
  •  Acceptance of the fact that for a successful project in the field of cell biology it is necessary to work in the laboratory 5 days a week plus sometimes weekends.

Main publications:
  •  Dashinimaev EB, Artyuhov AS, Bolshakov AP, Vorotelyak EA, Vasiliev AV. Neurons Derived from Induced Pluripotent Stem Cells of Patients with Down Syndrome Reproduce Early Stages of Alzheimer’s Disease Type Pathology in vitro. J Alzheimers Dis 2017;56:835-47. https://doi.org/10.3233/JAD-160945
  •  Artyuhov AS, Dashinimaev EB, Mescheryakova NV, Ashikhmina AA, Vorotelyak EA, Vasiliev AV. Detection of small numbers of iPSCs in different heterogeneous cell mixtures with highly sensitive droplet digital PCR. Mol Biol Rep 2019;46:6675-83. https://doi.org/10.1007/s11033-019-05100-2
  •  Artyukhov AS, Dashinimaev EB, Tsvetkov VO, Bolshakov AP, Konovalova EV, Kolbaev SN, et al. New genes for accurate normalization of qRT-PCR results in study of iPS and iPS-derived cells. Gene 2017;626:234-40. https://doi.org/10.1016/j.gene.2017.05.045


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